Pioneering single-stranded DNA for today’s innovations and tomorrow’s therapies.
Single-stranded DNA on large scales
We specialize in customized ssDNA solutions and large-scale manufacturing enabling your scientific innovations and breakthroughs.
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Long, scalable, versatile
- Sequence length up to 10,000 nt.
- Linear & circular single-stranded DNA.
- Large amounts, up to grams and more.
- High accuracy and endotoxin-purified, designed for use in both in vitro and in vivo applications.
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Strategic partner
Get quoteWe provide contract development and manufacturing services to support your project's development and commercialization, focusing on strategic long-term partnerships.
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Professional consulting
Get in touchOur scientific team tailors project plans to your needs and provides consistent support, working closely with you to advance your innovations.
Single-Stranded DNA (ssDNA) for Precision Gene Editing
Our ssDNA technology provides an ideal donor template for HDR-mediated gene knock-ins. When combined with gene editing tools like CRISPR-Cas, ssDNA templates offer enhanced knock-in efficiency and reduced toxicity. This is particularly advantageous for primary cells, such as T-cells, which are highly sensitive to double-stranded DNA (dsDNA) and achieve superior editing outcomes with ssDNA.
TCR-T and CAR T-Cell Therapy
Leverage the power of ssDNA to advance targeted cancer therapies involving large gene insertions. ssDNA enables precise and efficient integration of T-cell receptors (TCRs) or chimeric antigen receptors (CARs) in cell therapies while minimizing cellular toxicity, ensuring higher viability and functionality.
Gene Therapy
Unlock the potential of ssDNA in addressing genetic disorders like cystic fibrosis, sickle cell anemia, and Duchenne muscular dystrophy. ssDNA serves as a precise and reliable template for gene replacement and insertion therapies, offering transformative solutions for patients.
Agriculture and Food Technology
Revolutionize crop genomes with ssDNA to enhance pathogen resistance, boost productivity, and increase resilience. ssDNA-driven modifications contribute to sustainable agriculture and global food security.
Industrial Biotechnology
Optimize microorganisms for industrial applications with ssDNA, enabling more efficient production of biofuels, pharmaceuticals, and other valuable chemicals. This innovative approach supports the development of sustainable and scalable biotechnologies.
Custom ssDNA for DNA Origami
At gxstrands, we offer highly customizable single-stranded scaffold DNA designed specifically for DNA origami applications. Our ssDNA can be tailored to your needs with custom sequences and lengths ranging from 500 bases to 10 kb.
Whether you require small batches for early-stage testing or large-scale quantities for industrial production, our advanced facilities and streamlined processes ensure efficiency, quality, and scalability. This makes gxstrands the trusted partner for industries seeking reliable ssDNA supply.
Our ssDNA is also optimized for in vivo research applications, thanks to our rigorous endotoxin purification process, ensuring safe and high-performance results for your projects.
ssDNA for Diverse Applications
At gxstrands, we proudly support customers across a wide range of fields, providing high-quality ssDNA to drive innovation in groundbreaking projects and technologies.
Basic Molecular & Cell Research
Empower advanced molecular and cellular studies with gxstrands' single-stranded DNA, enabling breakthroughs in scientific research and discovery.
Diagnostics
Revolutionize disease detection with gxstrands' ssDNA, facilitating rapid and accurate identification of genetic markers for next-generation diagnostic tools.
Material Sciences
Explore novel applications of gxstrands' ssDNA in biomedicine and material sciences, including the creation of DNA hydrogels and other cutting-edge biomaterials.
